The Pathological Anatomy department performs histo-cytopathological diagnostics using morphological, immunohistochemical and molecular biology techniques (in collaboration with the Laboratory of Molecular Biology and Departmental Genetics).
Main conditions treated
- Breast disease
- Thyroid disease
- Gastrointestinal pathology
- Proctological pathology
- Urological pathology
- Head-neck pathology
- Obstetric-gynecological pathology
Services provided
- Histological diagnosis of endoscopic biopsies, agobiopsies of various organs, skin biopsies
- Histological diagnosis on operative specimens of surgical exeresis with histological typing of solid neoplasms of the different organs and apparatus on tissue included in paraffin
- Intraoperative diagnosis on frozen tissue (during surgery)
- Cytological diagnosis with aspiration needles (also with rapid on-site adequacy assessment)
- Urinary cytology (search for neoplastic cells in the urine)
- Cytological diagnostics on fluids and spills
- PAP TEST
It also deals with the characterization of neoplastic cells for the identification of molecular targets susceptible to therapy with specific drugs (“target therapy”). In particular:
- For breast cancers: immunohistochemical and in situ hybridization (SISH) study of the HER 2/neu gene, study of estrogen and progesterone receptors; study of PDL1 protein expression
- For tumors of the large intestine: immunohistochemical study of microsatellite instability (MSI) and mutational analysis of K-RAS, N-RAS, BRAF genes (in collaboration with the Departmental Molecular Biology Laboratory)
Scientific research activity
- Study being published: Anti-tumor immunity to patient-derived breast cancer cells by vaccination with interferon-alpha-conditioned dendritic cells (IFN-DC) in collaboration with the Istituto Superiore di Sanità.
- Study on the presence of microplastics in the placenta, in collaboration with Dr. A. Ragusa
Useful information
- Samples are accepted from Monday to Saturday from 08.30 to 19.00
- Urinary cytology on 3 samples: from Monday to Saturday from 08.30 to 13.00
- The request for slides and/or inclusions must be made from Monday to Saturday from 08.30 to 13.00
- Report collection: ground floor (courtyard). Monday to Friday from 07.00 to 18.45;
Saturday from 07.00 to 12.50. August and pre-holiday: Monday to Saturday from 07.00 to 13.00
Days and Hours of Access
Mon – Sat 08.00 – 19.30
Equipe Clinica
The Gemelli Isola Tiberina Hospital team is composed of a group of highly qualified and passionate experts, who work together to provide high quality care and innovative solutions. It is made up of doctors, surgeons, nurses and many other healthcare professionals specialised in a wide range of medical disciplines
